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Immunohistochemical Study of Peripheral Blood Mononuclear Cells in Sporadic Alzheimer's Disease and Dementia With Lewy Body
The subject uses cytof to analyze PBMC of sporadic AD and DLB, which is used to reveal the differences in immune characteristics of the two diseases at the single-cell level, build immune models for specific diseases, and define these two neurodegenerative diseases with high precision from the level of molecular immunity. To provide basis for further study of the immunohistochemical differences between the two diseases, and provide objective support for clinical diagnosis and differential diagnosis.
Age
55 - 100 years
Sex
ALL
Healthy Volunteers
Yes
Department of Psychiatry, First Affiliated Hospital of Zhejiang University
Hangzhou, Zhejiang, China
Start Date
April 1, 2022
Primary Completion Date
December 1, 2023
Completion Date
December 30, 2023
Last Updated
September 14, 2023
100
ESTIMATED participants
Detection of cytof in peripheral PBMC
BIOLOGICAL
Donepezil for patients with AD and DLB
DRUG
Lead Sponsor
First Affiliated Hospital of Zhejiang University
NCT07178210
NCT04123314
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