A Study to Assess the Safety and Tolerability of RC88 for Patients With Advanced Solid Tumours

Inclusion Criteria

• •1. All subjects must be ≥ 18 years at the first screening examination / visit.
• •2. Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 to 1.
• •3. Life expectancy of at least 12 weeks
• •4. Phase I must be histologically or cytologically confirmed and have failed standard therapy (disease progression after treatment) or are intolerant,unable to receive, or nonexistent to standard care,Patients with partial,advanced or metastatic malignant solid tumors;
• •5. Phase II-Advanced malignant solid tumor with MSLN expression
• •6. Patients with malignant pleural mesothelioma were assessed using mRECIST criteria, and those with other cancers were assessed using RECIST V1.1 criteria
• •7. Phase II-Mesothelin (MSLN) positive as confirmed by the central laboratory.
• •8. Adequate organ function
• •9. Voluntarily sign an informed consent form