Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Tufts University
With
University of North Carolina, Chapel Hill
Tufts Medical Center
University of Massachusetts, Worcester
Age
50–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age ≥ 50 years
Male or post-menopausal female (no menses in the last year)
Plasma phylloquinone \<1.0 nmol/L
Chronic knee discomfort based on affirmative response to the question "During the past 12 months, have you had pain, aching, or stiffness in or around your knee(s) on most days for at least one month?"
Kellgren-Lawrence (KL) grade 2-3 in at least one knee
Ability to understand study procedures and to comply with them for the entire length of the study
Ability to answer questions by phone
Ability to swallow capsules
You may not be if
KL grade 4 in at least one knee
Inability to walk
Cognitive impairment (based on a Montreal Cognitive Assessment Test score ≤ 17)
