Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Sao Paulo
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Current moderate or severe major depressive episode in bipolar I disorder assessed with Hamilton Depression Rating Scale (HAM-D) score ≥ 17 points.
Any appropriate first or second line pharmacological regimen in accordance with Canmat guidelines to treat a major depressive episode in bipolar I disorder:
Concomitant diagnosis of other neuropsychiatric disorders such as: schizophrenia, dementias, mental retardation, organic mental disorder, or epilepsy;
Acute suicide ideation (assessed by interview and clinical evaluation);
Acute psychotic depression (assessed by interview and clinical evaluation);
Suspected or confirmed pregnancy;
Women in breastfeeding;
Severe or unstable clinical disease;
Previous rTMS treatment;
Specific contraindications to TBS: previous epileptic seizures; change in electroencephalogram at some point in life; previous stroke; previous severe traumatic brain injury (with neurosurgery); metallic object on head (except mouth) as projectile piece, surgical clip, welding fragments; any implanted device (cardiac pacemaker, intravenous catheter).
Clareo Health | Evaluation of Theta-burst Stimulation Efficacy, Safety and Tolerability in Major Depressive Episodes of Bipolar I Disorder
