Lead Sponsor

Aerie Pharmaceuticals

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Have used, and/or desired to use artificial tears for DED symptoms within 6 months prior to Visit 1
•Within the last year from Visit 1, have a documented Schirmer test with or without topical anesthesia score ≥ 2 and ≤ 10 mm/5 min
•Within the last year from Visit 1, have documented symptoms of DED
•Corrected Visual Acuity (Snellen) 20/200 or better in both

•Use of artificial tears within 2 hours prior to Visit 1
•Use of ocular cyclosporine or other prescription ophthalmic solution for DED (e.g., Restasis®, Cequa®, Xiidra®) within 30 days of Visit 1 or anticipated use during the study period.
•Regular use of any topical ocular non-DED medication or use of a topical ocular non-DED medication within 2 hours of Visit 1
•Use of contact lenses in either eye within 7 days prior to the Screening visit or planned use during the study
•Punctal or intracanalicular plug present in either eyelid or anticipated plug insertion or occlusion at any time during the study.