Effect of Adding Metformin to Insulin in Uncontrolled Diabetic Patients During the 3rd Trimester of Pregnancy

Exclusion Criteria

• •Patients with type 1 diabetes
• •* Patients with congestive heart failure or a history of congestive heart failure
• •* Patients with renal insufficiency
• •* Patients with intolerance or hypersensitivity to metformin
• •* Patients having current significant gastrointestinal problems such as severe vomiting requiring intravenous fluids or hospitalization
• •* Presence of acute or chronic metabolic acidosis, including diabetic ketoacidosis, a history of diabetic ketoacidosis or history of lactic acidosis
• •* Patients with liver impairment
• •* Patients with known higher order pregnancies (twins, triplets, etc.)
• •* Patients having a known potentially fetal lethal anomaly