Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Stephanie Wang Zuo
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Postmenopausal (definition: No menses for 1 or more years or surgical menopause (bilateral oophorectomy). If there is a past history of hysterectomy, patient must be age 56 or older (95th percentile for age at menopause) or have laboratory evidence of menopause (ie. FSH \>30)
Meets criteria for recurrent urinary tract infections (UTIs) with 2 or more UTI in 6 months or 3 or more UTI in 1 year
May include patients who used vaginal estrogen previously if they have stopped use for 3 or more months prior to inclusion into study.
Patients must be recommended vaginal estrogen as part of normal clinical care for prevention of recurrent UTI
You may not be if
Current use of vaginal or oral estrogen products
Inability or refusal to use vaginal estrogen
Daily antibiotic use
Significant vaginal stenosis (eg. due to lichen sclerosis, radiation or obliterative prolapse surgery) that would prohibit use of a vaginal applicator (ie. genital hiatus \<1cm)
Inability to use vaginal applicator and without caregiver who can administer (eg. provider-managed pessary use, significant arthritis)
Frequent (1x weekly or more frequent) use of bladder instillations containing an antibiotic
Known hydronephrosis as a result of incomplete bladder emptying
Use of intermittent or indwelling urinary catheterization
Known bladder stones, mesh erosion into bladder, or foreign object in bladder
Unable to consent for self
Active treatment for an estrogen-dependent malignancy
Clareo Health | Periurethral vs Intravaginal Estrogen for Prevention of Recurrent Urinary Tract Infections
