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The Effects of Cold Habituation on Peripheral Blood Flow, Hand Function, and Thermal Comfort
In cold weather environments, blood flow to the extremities is significantly reduced, which severely impairs hand function and induces thermal discomfort. Prolonged or repeated cold exposure elicits an adaptive habituation response that is characterized by blunted skin vasoconstriction and thus may be an effective strategy to improve peripheral perfusion, reduce thermal discomfort, and maintain hand function during cold weather military operations. Since mission conditions often involve low ambient temperatures, countermeasures that reduce cold-induced decrements in hand function and thermal comfort are important to enhance Warfighter readiness in cold weather battlefield environments. The goals of this study are to 1) evaluate the effectiveness of cold habituation in improving skin blood flow, hand function, and thermal comfort during cold exposure and 2) identify the mechanisms that contribute to improvements in skin blood flow following habituation.
Participants (n=15, 18-39 yrs) will complete a preliminary cold air exposure (baseline testing) followed by 8 days of repeated cold air exposures with minimal clothing. The cold exposures will be 2 hours in duration and will be conducted in 8°C (46°F) conditions. Before and after the repeated cold exposures, participants will undergo hand function tests, assessments of thermal comfort, and skin blood flow testing.
Age
18 - 39 years
Sex
ALL
Healthy Volunteers
Yes
U.S. Army Research Institute of Environmental Medicine
Natick, Massachusetts, United States
Start Date
August 1, 2022
Primary Completion Date
September 13, 2024
Completion Date
September 13, 2024
Last Updated
December 26, 2025
16
ACTUAL participants
Repeated cold exposure
OTHER
Lead Sponsor
United States Army Research Institute of Environmental Medicine
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