Finding studies
Finding studies
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Lead
AstraZeneca
With
This study will be a randomized, open-label, 2-period, 2-treatment, single-dose, single-center, crossover study conducted at a single Clinical Unit. A total of 30 healthy male and female participants will be randomized to ensure that at least 26 participants are evaluable . The study will comprise of: * A Screening Period of maximum 28 days. * Period 1: single oral dose AZD4831 Formulation A or B on Day 1. * Period 2: single oral dose AZD4831 Formulation A or B on Day 1. * A final Follow-up Visit after the last administration of Investigational medicinal product (IMP) (14 days \[+ 3 days\] post final dose). There will be a minimum washout period of at least 14 days from the first dose of AZD4831. Participants will receive single doses of AZD4831 (2 different formulations) on 2 occasions under fasted conditions. Participants will be given the following treatments and randomly assigned to the treatment sequence(s): AB, BA * Treatment 1 (Reference), AZD4831 Formulation A, oral dosage form), fasted. * Treatment 2 (Test), AZD4831 Formulation B, oral dosage from), fasted.
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
