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Deep Neuromuscular Block on Postoperative Delirium in Lumbar Surgery | Clinical Trials | Clareo Health

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Deep Neuromuscular Block on Postoperative Delirium in Lumbar Surgery

Effect of the Deep Neuromuscular Block on Postoperative Delirium in Elderly Patients Undergoing Lumbar Surgery

NCT05453929•Korea University Guro Hospital

Summary

The effect of deep neuromuscular blockade (NMB) during spine surgery reduced postoperative pain and bleeding in recent studies. Therefore by reducing these two factors, which were the contributing factors for postoperative delirium, deep NMB is expected to reduce the postoperative delirium. This study was designed to determine whether the deep NMB lowered the incidence of delirium after lumbar surgery.

Eligibility

Age

70 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Aged 70 and more;
•Scheduled for an elective lumbar spine surgery;
•ASA physical status 1-3

Exclusion Criteria

•Diagnosed neuromuscular disorder;
•Contraindications to the study drug, e. g. known allergy or hypersensitivity, hypotension, bradycardia, higher grade atrioventricular block;
•Patient with pre-existing cognitive impairment or dementia

Locations (1)

Seok Kyeong Oh

Seoul, Gangnam-gu, South Korea

Key Dates

Start Date

September 16, 2021

Primary Completion Date

December 20, 2024

Completion Date

January 2, 2025

Last Updated

January 3, 2025

Enrollment

230

ACTUAL participants

Conditions

Lumbar Spine Disease

Interventions

Rocuronium for deep NMB

DRUG

Rocuronium for moderate NMB

DRUG