Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
CSL Behring
With
UBC Late Stage (UK) Ltd.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Chronic Active AMR group:
18 Years and older
Recipient of blood group system (ABO) compatible solitary kidney transplant between \[1Jan2013\] and \[1Jan2018\]
DSA antibodies within prior 6 months of the biopsy which confirmed chronic active AMR
Minimum of 3 years of follow up data following diagnosis of chronic active AMR (unless patient had died)
eGFR at time of diagnosis of chronic active AMR of \>25ml/min/1.73m2
Non-Chronic active AMR group:
Age 18 years or older
Recipient of ABO compatible solitary kidney transplant between \[1 Jan 2013\] and \[1Jan2018\]
No documented diagnosis of chronic active AMR during the data extraction period. Patients with other diagnoses such as TCMR, acute tubular necrosis, recurrence of primary kidney disease are also eligible. Patients may or may not have had biopsies.
Minimum of 4 years of follow up data since transplant (unless patient has died)
eGFR of \>25ml/min/1.73m2 at time of matching
You may not be if
Chronic active AMR group:
Recipient of a multi-organ transplant
ABO-incompatible transplant
Patient lost to follow up within the first 3 years post-diagnosis of chronic active AMR and whose allograft status (graft failure or patient death) is unknown.
Non-Chronic active AMR group:
Recipient of a multi-organ transplant
ABO-incompatible transplant
Patient lost to follow up within the first 4 years of transplant and whose allograft status (graft failure or patient death) is unknown.
Clareo Health | Assess Burden of Disease Among Kidney Transplant Recipients With Chronic Active Antibody Mediated Rejection
