The patient must have given their free and informed consent and signed the consent form
The patient must be a member or beneficiary of a health insurance plan
Patient with multiple sclerosis (EDSS score \< 7.5).
Moderate to severe dysuria (IPSS score \> 7) due to bladder sphincter dyssynergia confirmed by complete urodynamic workup.
Patient under stable treatment.
You may not be if
The subject is participating in another category 1 interventional study, or a trial involving a non-CE marked or CE marked off-label medical device or is in a period of exclusion determined by a previous study
The subject refuses to sign the consent
It is impossible to give the subject informed information
The patient is under safeguard of justice or state guardianship
Hypersensitivity to tamsulosin hydrochloride, including angioedema induced by the drug or any of the excipients.
History of orthostatic hypotension.
Severe hepatic impairment.
Concomitant treatment with diclofenac, warfarin, CYP3A4 inhibitors.
\- Patient with complete urinary retention at the time of the pre-inclusion consultation, requiring management by intermittent self-catheterization or, failing that, an indwelling bladder catheter from the outset.
Major medical or psychiatric illness that, in the opinion of the investigator, would place the subject at risk or could compromise compliance with the study protocol.
Presence of another neurological pathology (excluding MS).
Swallowing problems that compromise oral medication.