Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Priovant Therapeutics, Inc.
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
A diagnosis of dermatomyositis according to 2017 EULAR/ACR Classification Criteria for Idiopathic Inflammatory Myopathies
Adult subjects (18-75 years old)
Active muscle and skin disease at screening and baseline
Prior therapy OR current therapy with corticosteroids, hydroxychloroquine, and/or one non-steroid immunosuppressant
Weight \> 40 kg to \< 130 kg, and with a body mass index (BMI) \< 40 kg/m2.
You may not be if
Dermatomyositis with end-stage organ involvement
Dermatomyositis with irreversible muscle involvement
History of:
* Any lymphoproliferative disorder
* Active malignancy;
* History of cancer within 5 years prior to randomization (exceptions for basal cell carcinoma, squamous cell carcinoma, ductal carcinoma in situ of the breast, carcinoma in situ of the uterine cervix, or thyroid carcinoma.)
* Cancer-associated dermatomyositis
Overlap myositis/connective tissue disease (except for overlap with Sjögren's syndrome)
Participants at a risk of thrombosis or cardiovascular disease
Participants with a high risk for herpes zoster reactivation
