Probiotics in Systemic Lupus Erythematosus

1. Patients will be recruited and evaluated for eligibility. 2. Patients who met the eligibility criteria will be randomly assigned to either control or interventional group. 3. Patients in the control group will receive their standard therapy for 12 weeks and patients in the interventional group will receive their standard therapy plus one sachet daily of lacteol forte sachets for 12 weeks. 4. Collection of demographic data, full medication history, and full medical history will be performed at baseline and every 4 weeks. 5. Assessment of disease activity using SLEDAI-2K score, quality of life using the validated Arabic LupusPROv1.8 questionnaire, and Pain assessment using the validated Arabic version of the Short-Form McGill Pain Questionnaire will be performed at baseline and at the end of the study. 6. Safety and tolerability monitoring will be performed weekly using a side effect and/or adverse effect monitoring sheet. 7. Blood and urine samples for laboratory investigations will be withdrawn at baseline and at the end of the study.