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Sex Differences in E-cig Perception: Study 1 | Clinical Trials | Clareo Health

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COMPLETEDNANCT05432830

Sex Differences in E-cig Perception: Study 1

The primary objective is to examine the influence of sex on sensory effects, appeal, and reinforcing value of nicotine containing e-cigs in popular flavor components; sweet and cooling.

Lead sponsor: Yale University•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Yale University

Collaborators

National Institute on Drug Abuse (NIDA)

This study looks at the effect of sex on the sensory effects of flavor components in e-cigarettes. Regular combustible tobacco users will sample 3 different flavored e-cigarettes containing nicotine in a human lab paradigm.

Age

21 - 44 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•21-44 years old
•Able to read/write
•Current cigarette smoking
•Recent E-cig Exposure (\>/= 10 uses in past 6 mo.)
•Urine cot \>200ng/ml
•Willing to abstain from nicotine/tobacco 6-8hrs prior to lab session
•Not looking to quit

Exclusion Criteria

•Untreated chronic medical conditions
•Non-stable Rx medication
•Illicit drug use
•Pregnant, trying to become pregnant, breastfeeding
•Not fully vaccinated for Coronavirus (e.g. COVID-19)

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 28, 2026Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment66

Start dateApr 2024

Last updatedJan 28, 2026

Condition

Nicotine Addiction E-Cig Use Cigarette Smoking Sex Differences

Locations shown

Connecticut Mental Health Center

New Haven, Connecticut

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 28, 2026Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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