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RECRUITINGPhase 3NCT05430620

Intermittent Versus Continuous Surface O2 During HMP of DCD Kidneys

The aim of the study is to evaluate the feasibility of this bubble and surface oxygenation and to determine the optimal timing of surface oxygenation (continuous versus intermittent) as alternative fo...

Lead sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain•1 locations•View source on ClinicalTrials.gov

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Contacts

Tom Darius, Phd

CONTACT

003227642218 tom.darius@saintluc.uclouvain.be

Nathalie Staumont

CONTACT

003227642218 nathalie.Staumont@saintluc.uclouvain.be

Sponsors

Lead Sponsor

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Kidneys originating from deceased donors after circulatory death (DCD), category 3 and 5 (controlled) will be preserved from procurement until transplantation on hypothermic machine perfusion conditions and prospectively randomized into 2 study groups: 1) intermittent surface oxygenation during HMP (surface oxygenation interrupted during organ transport (2-4h)(I-HMPO2 group), and 2) continuous surface oxygenation during HMP (surface oxygenation during the whole machine preservation period included organ transport)(C-HMPO2 group).

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Listed for a renal transplantation due to end stage renal disease
•Willingness to comply with the protocol procedures for the duration of the study included scheduled follow-up visits and examinations.

Exclusion Criteria

•Multi-organ recipients
•Dual kidney transplantation

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 23, 2024Terms

Trial snapshot

StatusRECRUITING

PhasePHASE3

Enrollment60

Start dateMar 2022

Last updatedMay 23, 2024

Condition

Delayed Graft Function Kidney Transplant; Complications Ischemia Reperfusion Injury Mitochondrial

Locations shown

Cliniques Universitaires Saint-Luc

Brussels, Woluwé-Saint-Lambert

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 23, 2024Data synced to Clareo: May 3, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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