Spinal Cord Stimulation in Spinal Muscular Atrophy

Exclusion Criteria

• •1. Subject has deformation of the spinal canal preventing lead implantation as judged by the study neurosurgeon
• •2. Subject has size of spinal canal that is insufficient for lead implantation as judged by the study neurosurgeon
• •3. Subject has moderate or severe joint contractures that would affect ability to perform study measures
• •4. Subject has severe behavioral or cognitive problems that preclude participation in the study, in the opinion of the investigator
• •5. Subject has previous or ongoing medical condition, medical history, physical findings or laboratory abnormalities that could affect safety of anesthesia or the procedures, make it unlikely that intervention or follow-up will be correctly completed or impair the assessment of study results, in the opinion of the investigator
• •6. Female subjects are pregnant or breastfeeding
• •7. Subject has severe claustrophobia
• •8. Subject is on anticoagulant, anti-spasticity or anti-seizure medication within 4 weeks of lead implantation or requires these medications during the treatment phase of the study
• •9. Subject has medical implant that precludes magnetic resonance imaging