Transcranial Direct Current Stimulation (tDCS) in Human Subjects With PTSD Receiving an Exposure-based, Behavioral Therapy

Exclusion Criteria

• •1. History of epilepsy or seizures.
• •2. History of significant intracranial pathology (e.g., severe traumatic brain injury) or neurological disorder (e.g., Stroke, Multiple Sclerosis, Amyotrophic Lateral Sclerosis, Alzheimer's, Dementia, Parkinson's, and/or Huntington's).
• •3. History of skin condition (e.g., eczema, psoriasis) where electrodes will be applied.
• •4. Electronic implants in the body that could be susceptible to electrical current (e.g., cardiac pacemaker, cochlear implants, medical pump).
• •5. Metallic objects other than dental appliances/fillings near the site of stimulation
• •6. Current manic episode or psychotic symptoms requiring immediate stabilization or hospitalization (as determined by clinical judgement).
• •7. Current moderate or severe substance use disorder.
• •8. Suicidality and/or psychiatric risk requiring immediate intervention or a higher level of care than can be provided by the study treatment.
• •9. Change in anticonvulsive or benzodiazepine medication regimen in the past month.
• •10. History of adverse effects to previous tDCS or other brain stimulation technique.
• •11. Concurrent engagement in another brain simulation technique or trauma-related psychotherapy for PTSD.
• •12. Currently pregnant or breastfeeding.