Effect of Airway Pressure Release Ventilation on Right Ventricular Function Assessed by Transthoracic Echocardiography

Exclusion Criteria

• •1. Aged less than 18 years old or older than 80 years old
• •2. Obese patients with BMI≥35kg/m2;
• •3. Pregnant and lactating women
• •4. The expected time of invasive mechanical ventilation is expected to be less than 48h
• •5. Neuromuscular disease known to require prolonged mechanical ventilation
• •6. Severe chronic obstructive pulmonary disease
• •7. Intracranial hypertension
• •8. Bullae or pneumothorax, subcutaneous emphysema, mediastinal emphysema
• •9. extracorporeal membrane oxygenation(ECMO) has been performed when entering the ICU
• •10. Refractory shock
• •11. Severe cardiac dysfunction (New York Heart Association class III or IV, acute coronary syndrome or persistent ventricular tachyarrhythmia), right heart enlargement due to chronic cardiopulmonary disease, cardiogenic shock or heart enlargement postoperative;
• •12. Failure to sign informed consent