COMPression of Left Main coRonary artEry in patientS With Pulmonary Arterial Hypertension aSymptomatIc fOr aNgina

Exclusion Criteria

• •Severe chronic kidney disease \[Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) estimated glomerular filtration rate \<30 ml/min) or need for dialysis
• •Major allergy to iodinated contrast agent
• •Intolerance or allergy to acetylsalicylic acid or clopidogrel
• •History of stroke or transient ischemic attack in the last 6 months or a history of intracranial haemorrhage
• •Known cerebral arteriovenous malformation or aneurysm
• •Known moderate or severe hepatic insufficiency (Child Pugh B or C)
• •Thrombocytopenia (\<100.000/μL) or anemia (hemoglobin \<10 g/dL)
• •Active bleeding or factors which, in the investigator's judgment, significantly increase the risk of bleeding
• •Major surgery in the past 30 days
• •Cancer in the active phase
• •Pregnancy or breastfeeding
• •Patient prognosis \<1 year in the opinion of the investigator
• •Any condition that increases the risk of non-compliance or of being lost to follow-up
• •Patients who have already undergone a LMCA angioplasty
• •Failure to obtain informed consent