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Evaluation of Ovarian Reserve in Women With Subclinical Hypothyrodism in Reproductive Age
This study aimed to evaluate the potential association of subclinical hypothyrodism and ovarian reserve in reproductive age in age groups more than 35 and age groups less than 35 using retrospective study included women with subclinical hypothyrodism and controls .Evaluation of potential association of antithyroid antibodies positivity on ovarian reserve Primary outcome: Measure the association of SCH with ovarian reserve markers (basal FSH ,LH/basal AFC /AMH)
Thyroid dysfunction is one of the commonest disorders in women of reproductive age .there is association between subclinical hypothyrodism and infertility and ovarian reserve .It's known that subclinical hypothyrodism can be associated with reduced ovarian reserve in women more than 35 years old .Aclear association between subclinical hypothyrodism and ovarian reserve not established in reproductive age in women less than 35 .This retrospective study investigate serum thyroid hormone /Antithyroid hormone ,ovarian reserve markers (basal FSH,AMH,Antral follicle count on day 2-4/prolactin level .
Age
13 - 45 years
Sex
FEMALE
Healthy Volunteers
No
Assiut Medical School
Asyut, Egypt
Start Date
January 1, 2016
Primary Completion Date
January 1, 2020
Completion Date
August 1, 2023
Last Updated
June 8, 2022
300
ESTIMATED participants
retrospective charts reviewing
BEHAVIORAL
Lead Sponsor
Assiut University
NCT06928337
NCT06799507
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06584994