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RECRUITINGNANCT05409573

Feasibility of End-tidal Oxygen Concentration Monitoring During Preoxygenation for Intubation in the Intensive Care Unit.

Intubation is a common procedure in the intensive care unit. Hypoxemia is the most frequent complication of this procedure. Monitoring the end-tidal of oxygen is recommended in operating room (OR). E...

Lead sponsor: Centre Hospitalier Régional d'Orléans•1 locations•View source on ClinicalTrials.gov

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Contacts

Mai-Anh NAY, PH

CONTACT

+33238575253 mai-anh.nay@chr-orleans.fr

Sponsors

Lead Sponsor

Centre Hospitalier Régional d'Orléans

This is a prospective non-comparative interventional study. A double monitoring of EtO2 will be performed during the procedure of intubation (from the beginning of the preoxygenation to the success of intubation): * In the pharynx (via a nasopharyngeal catheter) for the needs of the study * On the facemask (as the practice in the OR) The duration of the study will not exceed one hour, including the installation of the devices.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Age ≥ 18 years
•Requiring an intubation in ICU for acute respiratory failure defined as a respiratory rate ≥ 25/min or clinical signs of respiratory distress or hypoxemia defined as oxygen requirement ≥ 15L/min or FiO2 ≥80% to maintain SpO2 ≥92% or a PaO2/FiO2 ratio \<100 mmHg
•With preoxygenation by noninvasive ventilation

Exclusion Criteria

•Intubation for cardiac arrest
•EtO2 monitoring not available
•Pulsed oxygen saturation monitoring specific for the study not available
•Preoxygenation by high-flow nasal oxygen therapy or bag-mask ventilation
•Allergy to lidocaine (for local nasal anesthesia)
•Previously
•Patient not affiliated or excluded from social protection, or under law protection (namely minors, pregnant or breastfeeding women, persons deprived of their liberty by court or administrative decision)
•Previously included in the study

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 29, 2026Terms

Trial snapshot

StatusRECRUITING

PhaseNA

Enrollment30

Start dateDec 2022

Last updatedJan 29, 2026

Condition

Locations shown

CHR d'ORLEANS

Orléans

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 29, 2026Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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