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Persona MC vs PS RCT With ROSA | Clinical Trials | Clareo Health

RECRUITINGNA

Persona MC vs PS RCT With ROSA

Randomized Control Trial Comparing Zimmer Biomet Persona Medial Congruent Versus Posterior Stabilized Total Knee Arthroplasty for Treatment of Knee Arthritis Using the ROSA Knee System

NCT05391828•NYU Langone Health

View on ClinicalTrials.gov

Summary

A randomized, controlled study comparing two total knee implant devices, Persona medial congruent (MC) vs posterior stabilized (PS). These surgeries will be performed using the ROSA robotic system. Patients will be followed up to 5 years.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Patients ≥18 years of age
•2. Patients scheduled an elective primary TKA for a diagnosis of osteoarthritis or inflammatory arthritis using the ROSA Knee System.
•3. Patient is willing to cooperate and follow study protocol and visit schedule
•4. Subject has access to a device is capable of pairing to the Apple Watch, supporting application updates and is compatible with the mymobility App.

Exclusion Criteria

•1. Patient is pregnant
•2. Patient is unable to provide written consent
•3. Revision TKA
•4. History of prior infection in the affected knee
•5. History of prior open surgery with significant hardware in place on the affected knee (i.e. prior distal femur or proximal tibia fracture or osteotomy)
•6. Preoperative diagnosis of post-traumatic arthritis, avascular necrosis, or fracture

Locations (1)

NYU Langone Health

New York, New York, United States

Key Dates

Start Date

September 27, 2023

Primary Completion Date

December 1, 2025

Completion Date

December 1, 2026

Last Updated

July 30, 2025

Enrollment

200

ESTIMATED participants

Conditions

Total Knee Arthroplasty

Interventions

Zimmer-Biomet Persona Medial Congruent (MC) Bearing Design

DEVICE

Zimmer-Biomet Persona Posterior-Stabilized (PS) Bearing Design

DEVICE

Contacts

Vinay Aggarwal, MD

CONTACT

202 250 0679 Vinay.Aggarwal@nyulangone.org

Daniel Waren

CONTACT

954 559 2251 Daniel.Waren@nyulangone.org

Use of Cryopressotherapy in Patiens Undergoing Total Knee Replacement to Improve Clinical Outcome

NCT07456787

Total Knee Arthroplasty\(TKA\)Osteoartrosi

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RECRUITINGNA

Mako Cementless TKA vs Mako Cemented TKA

NCT06929871

Total Knee ReplacementTotal Knee Replacement Surgery+2 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 30, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Persona MC vs PS RCT With ROSA

Inclusion Criteria

Exclusion Criteria

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