Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of California, San Francisco
Healthy volunteer subjects aged 40-60 will receive a standardized weight-based 10-minute remifentanil infusion protocol to achieve a peak estimated remifentanil effect site concentration of approximately 6 ng/mL. Pupillary measures will be taken at baseline and regular time intervals during and after the infusion, over a period of 35 minutes.
Age
40–60
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Healthy, BMI \< 35 kg/m2
You may not be if
current or recent opioid use
opioid or other substance use disorder
known or suspected OSA or sleep disordered breathing
ischemic heart disease, heart failure or symptomatic arrhythmia history
ocular disease or previous eye surgery
active use of alpha adrenergic blockers, anticholinergic medications,
active use of antidepressant or mood stabilizing medications
active use of phosphodiesterase inhibitors
use of stimulant or appetite suppressant medications
active use of antihypertensive or antiarrhythmic medications
