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Potassium Citrate and Crystal Light Lemonade | Clinical Trials | Clareo Health

ACTIVE_NOT_RECRUITINGNA

Potassium Citrate and Crystal Light Lemonade

Assessing the Effects of a Commercial Lemonade Beverage and Potassium Citrate on Urinary Stone Risk Factors

NCT05389995•Northwestern University

Summary

To define the effect of crystal light, potassium citrate, or both on urinary stone risk factors in patients with a history of stone and hypocitraturia/low pH

Eligibility

Age

18 - 80 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Men and women between age 18-80 years
•2. Willing to follow experimental protocol
•3. Willing to complete 24-hour urine collections (three total)
•4. Willing to sign the informed consent form
•5. Completed Litholink Collection with blood work with results
•a. hypocitraturia OR aciduria i. Hypocitraturics must meet definition of \< 450 mg/day for men \< 550 mg/day for women.
•b. Low urine pH must be less than 5.6 c. potassium, BUN, creatinine, eGFR and hemoglobin A1c within normal limits

Exclusion Criteria

•1. Patients with severe hypocitraturia \< 200 mg/day (men or women)
•2. Patients with hyperkalemia, uncontrolled diabetes, chronic kidney disease, adrenal insufficiency, delayed gastric emptying (or drug induced delayed gastric emptying), peptic ulcer disease, or active UTI
•3. Patients with distal renal tubular acidosis or medication induced RTA (e.g. carbonic anhydrase inhibitor, topiramate)
•4. Members of vulnerable patient populations
•5. Allergies to ingredients in crystal light
•6. Patients lacking decisional capacity

Locations (1)

Northwestern University

Chicago, Illinois, United States

Key Dates

Start Date

August 1, 2022

Primary Completion Date

April 1, 2025

Completion Date

January 31, 2027

Last Updated

January 21, 2026

Enrollment

ESTIMATED participants

Conditions

Kidney Stone

Interventions

Potassium citrate

DRUG

Crystal light

DRUG

Potassium citrate + crystal light

DRUG

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RECRUITINGNA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 21, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Potassium Citrate and Crystal Light Lemonade

Inclusion Criteria

Exclusion Criteria

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