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The Effect of Oral Kavalactones on Sleep and Cortisol in a Cohort of Healthy Adult Males Preparing for Military Special Forces Training
This research study is being done to better understand the effects of kava supplementation on sleep quality and salivary cortisol in the context of the acute physical and psychological stress of military special forces preparation training. Kava is a botanical dietary supplement derived from the plant Piper methysticum. Cortisol is a hormone associated with stress.
Acute physical and behavioral stress can interfere with sleep quality and cause cortisol to increase. This can have a negative impact on quality of life and the ability to perform optimally. Kava, derived from the rootstumps of the Piper methysticum plant, has been utilized traditionally, socially, and for its calmative properties by the peoples of Oceania for millennia. Kava has been available as a dietary supplement for decades. Participants in this placebo-controlled cross-over study will be enrolled concurrently with a special operations prep class during which they will be experiencing significant physical and mental stressors. Participants will be divided into two arms - one taking kava and the other taking placebo for the first two-week phase of the study. Following a washout and cross-over, participants will switch what they are taking for the second two-week phase.
Age
18 - No limit years
Sex
MALE
Healthy Volunteers
Yes
Performance First
Virginia Beach, Virginia, United States
Start Date
May 11, 2022
Primary Completion Date
July 1, 2022
Completion Date
October 9, 2022
Last Updated
October 13, 2022
15
ACTUAL participants
Kava (Piper methysticum) extract
DIETARY_SUPPLEMENT
Lead Sponsor
Thorne HealthTech, Inc
Collaborators
NCT01778504
NCT06430957
Data Source & Attribution
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