Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University at Buffalo
With
Volcano Corporation
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age 18-65 years
* EDSS 0-6.5
* Diagnosis of relapsing MS according to the McDonald criteria (Polman et al., 2005)
* Be on treatment with currently FDA approved disease-modifying treatments
* Evidence of ≥2 sonographic parameters of suspicious abnormal extracranial cerebral venous outflow (see Table 1 background and 1.5 section)
* Demonstration of venous occlusive disease on cervical MRV
* Normal renal function: creatinine clearance level of \>60:
Constant= 1.23 for men; 1.04 for women
You may not be if
• Relapse, disease progression and steroid treatment in the 30 days preceding study entry
* Pre-existing medical conditions known to be associated with brain pathology (e.g., neurodegenerative disorder, cerebrovascular disease, positive history of alcohol abuse, etc.)
* Severe peripheral chronic venous insufficiency
* Abnormal renal function
* Contrast allergy (anaphylaxis)
* Not accepting to undergo the endovascular treatment
