Personalized Fiber and Insulin Sensitivity

Exclusion Criteria

• •Type 2 diabetes mellitus (defined as fasting plasma glucose ≥ 7.0 mmol/L and 2h glucose ≥ 11.1 mmol/L)
• •Gastroenterological diseases or abdominal surgery;
• •Cardiovascular diseases, cancer, liver or kidney malfunction, disease with a life expectancy shorter than 5 years;
• •Abuse of products; alcohol and drugs, excessive nicotine use defined as \>20 cigarettes per day;
• •Plans to lose weight or following of a hypocaloric diet;
• •Regular supplementation of pre- or probiotic products, use of pre- or probiotics 3 months prior to the start of the study;
• •Intensive exercise training more than three hours a week;
• •Use of any medication that influences glucose or fat metabolism and inflammation (i.e. NSAIDs);
• •Regular use of laxation products;
• •Use of antibiotics in the last three months (antibiotics use can alter substantially the gut microbiota composition).
• •Follow a vegetarian diet.