Men aged 18 years or older with histologically proven prostate carcinoma
Imaging stage T3b (as defined on mpMRI) N0M0
Intraprostatic lesion visible on MRI
Capable of giving informed consent
You may not be if
History of radiotherapy to the pelvis or transurethral resection of the prostate (TURP)
Contraindications for MRI according to the guidelines of the local department of Radiology, inability to lay on a treatment table for 45-60 minutes or severe claustrophobia
Absence of pre-treatment PSMA PET CT
WHO performance score \> 2
International Prostate Symptom Score ≥ 15
PSA \> 30
Prostate volume \>100c
Clareo Health | Addition of a Focal Boost in External Beam Radiotherapy for Locally Advanced Prostate Cancer by Online Adaptive MR-guided Radiotherapy
