Efficacy Evaluation of Hydrolyzed Collagen Peptide on Knees, Hips, and Ankle Pain in Osteoarthritis

Exclusion Criteria

• •1. Who have atopic constitution or asthma and/or known allergy for bovine derived collagen products and/or other any of the excipients of the product.
• •2. Who have hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucosegalactose malabsorption.
• •3. Who have an active rheumatoid arthritis or any other inflammatory arthritic condition that researchers consider non appropriate.
• •4. Who have Diabetes Mellitus.
• •5. Who have the use of oral retinoids or oral steroids in the 6 months prior to initiation of the study.
• •6. Who have current participation in another clinical study, or participation in a relevant study within 3 months.
• •7. Who have any history or presence of serious or life-threatening conditions of cardiovascular, neurological, haematological, hepatic, gastrointestinal, renal, pulmonary, endocrinological, metabolism or psychiatric disease, any type of porphiria.
• •8. Who have the presence or history of malabsorption or any gastrointestinal surgery except appendectomy or except herniotomy.
• •9. Who are planned to go or already went under a joint-related reconstructive surgery,
• •10. For female volunteers, who had undergone, or planned to undergo, pregnancy or breastfeeding.
• •11. Who have current or regular intake of NSAIDS, contraceptives, hormones, obesity drugs, absorption inhibitors or antidepressants
• •12. Who are suspected to have a high probability of non-compliance to the study procedure and/or completion of the study according to the investigator's judgment.
• •13. Who have history of drug abuse.
• •14. Who have relationship to the investigator.