Oscillation and Lung Expansion (OLE) Therapy for Treatment of Neuromuscular Disease (NMD) Patients

Inclusion Criteria

• •Documented diagnosis of neuromuscular disease (NMD) or neurological disorder.
• •Age 5 to 80 years.
• •History of one or more respiratory exacerbations in the past 6 months or two or more respiratory exacerbations in the past 12 months, which required unplanned or unscheduled medical intervention.
• •Ability to perform Oscillation and Lung Expansion (OLE) therapy as directed.
• •Signed informed consent (and assent if minor patient).
• •Patients who meet any of the following criteria will be excluded from the study:
• •Diagnosis with rapidly progressing NMD such as certain types of Motor Neuron Disease (MND).
• •Requirement for continuous mechanical ventilation.
• •Anticipated requirement for respiratory related hospitalization within the next six months.
• •History of pneumothorax within the past 6 months.
• •History of hemoptysis requiring embolization within past 12 months.
• •Pregnancy.
• •Home use of OLE therapy within the past 12 months.
• •Inability or unwillingness to perform OLE therapy or study procedures as required.