Age

18–65

Sex

ALL

Healthy volunteers

Not accepted

Clinically definite multiple sclerosis (revised McDonald criteria 2017)
Expanded Disability Status Scale (EDSS) below 6.0
Digit span backwards z-score between \[-3 and -0.5\] standard deviations below the median of the normative values
Age between 18 and 65
Able to safely perform motor rehabilitation in the home situation (assessed by rehabilitation physician and/or occupational or physiotherapist)

Cognitive rehabilitation within six months before inclusion
Inpatient multidisciplinary rehabilitation program within three months before inclusion or planned inpatient program during trial
Start of or switch in immunomodulator treatment within three months before inclusion
Less than one month post-exacerbation
Major psychiatric or medical disorder that could influence cognitive functions
Combined vision with optimal correction below 0.6 on Snellen Visual Acuity Test
Unable or unwilling to undergo EEG or MRI
Refusing informed consent

Cognitive-motor Telerehabilitation in MS