Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1;
Historically and radiologically confirmed colorectal cancer peritoneal metastasis except for appendical origin;
Tolerable to scheduled chemotherapy;
No evidence of extraperitoneal metastases at enrollment;
Resectable disease determined by radiological and laparoscopy/laparotomy;
No systematic therapy within 6 months before enrollment;
Tolerable to cytoreductive surgery.
You may not be if
Without adequate organ function (e.g. :neutrophil countt≤1.5×10\^9/L, or platelets≤75×10\^12/L，or hemoglobin\<90g/L, or aminotransferase、aspartate aminotransferaseAST\<2.5ULN, or total bilirubin\<1.5ULN, or creatinine\<1.5ULN;
Emergency surgery;
Recent thromboembolic event or cerebrovascular disease (12 months before enrollment);
