Multimodal Prehabilitation To Improve The Clinical Outcomes Of Frail Elderly Patients With Gastric Cancer

Inclusion Criteria

• •1. Aged 65-85 years;
• •2. Karnofsky performance score ≥70 or Eastern Cooperative Oncology Group (ECOG) performance status score ≤2;
• •3. G8 score ≤14;
• •4. Endoscopic biopsies were pathologically confirmed as gastric adenocarcinoma;
• •5. Patients with cT1-4aN0-3M0 by endoscopy, imaging evaluations of CT and MRI, and possibility of gastric resection;
• •6. Received general anesthesia or combined spinal-epidural anesthesia (Surgery was performed by either laparotomy, laparoscopy or robotic-assisted laparoscopic);
• •7. Date of surgery ≥2 weeks from baseline (T0) assessment;
• •8. Physical conditions could meet the requirements of exercise training, and no severe concomitant disease;
• •9. All subjects had to be willing and able to comply with study protocol and were informed adequately that they maintained the right to drop out of the study at any time.