Impact of Structural and Myelin Abnormalities on Cognitive Impairments in Recent-onset Schizophrenia - Before and After Lurasidone Treatment (MARYLU)

Exclusion Criteria

• •presence of other psychiatric and/or neurological diagnoses
• •previous antipsychotic treatment, except for patients that have been treated with other antipsychotics for less than a month and that have not been treated in the two weeks preceding the beginning of the trial, who are considered eligible.
• •contraindications to lurasidone treatment (as per summary of product characteristics)
• •intellectual disability
• •alcool or substance abuse in the previous 6 months
• •presence of absolute or relative contraindications to MRI
• •underage patients
• •no negative pregnancy test or no use of a highly efficient contraceptive method
• •pregnancy (if a patient becomes pregnant during the course of the study, the subject will be excluded from the study)
• •presence of psychiatric and/or neurological disorders
• •family history of psychiatric disorders in 1st-degree relatives
• •intellectual disability
• •other medical conditions at the time of the study
• •family history of hereditary neurological diseases
• •alcool or substance abuse
• •presence of absolute or relative contraindications to MRI
• •underage patients
• •no negative pregnancy test or no use of a highly efficient contraceptive method
• •pregnancy (if a subject becomes pregnant during the course of the study, the subject will be excluded from the study)