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Intercostal Nerve Cryotherapy in Patients Undergoing Minimally Invasive Pulmonary Resection | Clinical Trials | Clareo Health

ACTIVE_NOT_RECRUITINGNA

Intercostal Nerve Cryotherapy in Patients Undergoing Minimally Invasive Pulmonary Resection

Randomized Trial of Intercostal Nerve Cryotherapy in Patients Undergoing Minimally Invasive Pulmonary Resection

NCT05348447•Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

View on ClinicalTrials.gov

Summary

This is a research study designed to test whether a treatment called Intercostal Nerve Cryotherapy is an effective way to help control post-surgical pain for patients undergoing minimally invasive pulmonary resection. There are two treatment groups in this study, a cryotherapy group and control group. Cryotherapy is a method of controlling pain by freezing nerves between the ribs that would transmit pain impulses to the brain.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Patients 18 year and older.
•2. Undergoing elective minimally invasive (VATS or robotic) lung resection for nodules (wedge resection, segmentectomy, lobectomy).
•3. Performance status of 1 or 2.

Exclusion Criteria

•1. Patients with ejection fraction less than 40%
•2. Patients with creatinine greater than 1.5.
•3. Patients with Child's B or C cirrhosis
•4. Patients on chronic narcotics for other reasons
•5. Patients diagnosed with fibromyalgia
•6. Patients who had previous thoracic surgery on the same side.
•7. Patients who cannot communicate in English.
•8. Patients unable to provide informed consent for the study.

Locations (1)

AHN Allegheny General Hospital

Pittsburgh, Pennsylvania, United States

Key Dates

Start Date

April 21, 2022

Primary Completion Date

March 20, 2026

Completion Date

March 20, 2026

Last Updated

February 13, 2026

Enrollment

110

ACTUAL participants

Conditions

Cryotherapy EffectPain, Postoperative

Interventions

cryoanalgesia

DEVICE

Standard of Care Pain Control

OTHER

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 13, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Intercostal Nerve Cryotherapy in Patients Undergoing Minimally Invasive Pulmonary Resection

Inclusion Criteria

Exclusion Criteria

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