Observational Study to Evaluate the Influence of Undercast Material Types on Skin Microbiome

Exclusion Criteria

• •1. Subject \<18 years of age
• •2. Pregnancy, breast feeding
• •3. Participation in other clinical trials
• •4. Patient is neither physically nor mentally able to participate in this study
• •5. Non-intact skin in treatment area (including dermatological issues)
• •6. Patients with impaired (e.g. Cortisone skin, extremely dry skin, parchment skin) or damaged skin with either a surgical wound or a traumatic wound
• •7. Medical treatment prior casting which could influence the microbiome
• •8. Known Blood Circulatory Diseases
• •9. Known Lymphedema or any general disorder of the lymphatic system
• •10. Known Osteoporosis
• •11. Known Diabetes
• •12. Knowing of one of the following illnesses that might require regular systemic medication: cancer, rheumatic disease
• •13. Intolerability or documented allergies against cast materials
• •14. Subjects with not "normal" (unusual) hygienic behavior
• •15. Suspected drug addiction or alcohol abuse
• •16. Patients diagnosed HIV-positive or with infectious hepatitis based on self-declaration by subjects