Pharmacokinetics and Bioavailability of Curcumin UP 30 Capsules in Healthy Adult Subjects

Exclusion Criteria

• •Abnormal conditions judged by clinicians to be clinically significant, which the research doctor considers not suitable for participants;
• •A positive test results for hepatitis B virus（HBV）, hepatitis C virus（HCV）, HIV or syphilis;
• •Those who have a history of specific allergies or allergies, or those who are known to be allergic to curcumin components or the like;
• •A history of alcoholism ;
• •A history of dysphagia or any gastrointestinal disease that affects drug absorption;
• •Female subjects are breastfeeding during the screening period or clinical trials or have a positive pregnancy test result;
• •Those who have a positive drug screening test or have a history of drug abuse in the past five years or have used drugs in the 3 months before taking the drug;
• •Those who smoked more than 5 cigarettes a day on average in the 3 months before the test;
• •Donate blood or blood loss ≥ 400ml within 3 months before taking the study drug;
• •Have a history of surgery or have taken the study drug within 3 months before taking the study drug;
• •Any prescription drugs taken within 14 days before taking the study drug;
• •Any over-the-counter medicines, herbal medicines or prescribe products taken within 7 days before taking the study drug;
• •Have taken a special diet or strenuous exercise or other drugs that affect the study within 48 hours before taking the study drug Those with factors such as absorption, distribution, metabolism, and excretion;
• •Consume chocolate, any caffeine-containing or xanthine-rich beverage or food (such as animal liver) within 48 hours before taking the study drug;
• •Those who have taken any alcohol-containing products within 24 hours before taking the study medication, or those who have been tested positive for alcohol;
• •Subjects judged by other researchers to be unsuitable to participate.