ERAdicate S. Aureus in Patients With Bacteremia and Endocarditis

Exclusion Criteria

• •Previous receipt of LSVT-1701 or CF-301 (exebacase)
• •Known hypersensitivity to kanamycin or other aminoglycosides
• •Treatment with any potentially effective (anti-S. aureus) systemic antibiotic for \> 96 hours within 7 days before enrollment. Exception: Persistent S. aureus bacteremia after 96 hours of prior appropriate systemic antistaphylococcal antibiotic, and/or resistance to the prior systemic antibiotic
• •Treatment with dalbavancin or oritavancin within the previous 90 days
• •Known or suspected brain abscess or meningitis
• •Community acquired pneumonia, nosocomial pneumonia because of pathogens other than S. aureus, or known polymicrobial bacteremia
• •Presence of an intravascular infection source or extravascular material that cannot be removed within 96 hours after enrollment