Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Peking University
Age
18–70
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Written informed consent
Core biopsy confirmed unicentric primary invasive triple-negative or HER2-positive breast cancer. Multifocal or multicentric tumors allowed only if breast-conserving surgery is deemed feasible.
At least 18 years of age
Initial tumor stage cT1c-T3N0M0 prior to NACT. cN0 stage established by clinical examination and ultrasonography
In cases with suspicious lymph node, a negative core biopsy or fine needle aspiration (FNA) biopsy of the sonographically suspected lymph node is required
Standard NACT with evident radiologic response
Planned breast-conserving surgery with postoperative external whole-breast irradiation
You may not be if
History of previous malignancy
Histologically proven N1 patients, patients with distant metastasis (M1)
Pregnant or lactating patients
Inflammatory breast cancer
Radiologically non-responsive after NACT
Mastectomy planned after NACT
planned intraoperative radiotherapy (e.g. Intrabeam) or postoperative partial breast irradiation (e.g. multicatheter technique) alone; both procedures are allowed as boost techniques
Written informed consent not obtained
Clareo Health | Selective Omission of Axillary Surgery in Triple-negative and HER2-positive Breast Cancer After NACT
