Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Peking Union Medical College Hospital
Age
18–50
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Normal weight (18.5 ≤ BMI \< 24 kg/m2) or obese (28 ≤ BMI \< 35 kg/m2);
Aged 18 to 50 years old;
Han nationality;
Able to follow the weight-loss prescription;
Able to sign consent independently;
Definition of Weight cycling: Loss weight more than once in the past 3 years, and weight regain exceeds 5% or more of the baseline weight of losing weight.
You may not be if
Bodyweight has changed more than ±10% in the past year;
Taking drugs known to affect body weight (orlistat, GLP-1 receptor agonists, etc.);
Taking drugs known to affect glucolipid metabolism (such as sulfonylureas, biguanides, acarbose, or insulin) have been taken in the past 6 months or at present; Lipid-lowering drugs such as statins, bate, niacin, and ezetimibe; Diuretics, β -blockers and other antihypertensive drugs; Glucocorticoid, thyroid hormone, etc.);
Women who are currently pregnant or nearly 3 months breastfeeding;
With serious eating disorders or vigorous exercise to lose weight;
Hard physical workers;
History of serious cardiovascular disease;
Acute, chronic, or active gastrointestinal diseases;
Serious systemic diseases;
History of serious mental disorders;
Cancer or active tumor;
Secondary obesity or drug obesity patients: including hypothalamic obesity, pituitary obesity, hypercortisolism, and hypogonadism obesity;
Severe liver dysfunction (ALT, AST, ALP, and TBil \> the upper limit of 2.5 times reference value);
Chronic kidney disease (eGFR \< 60 mL/min/1.73 m2 or eGFR \< 90 mL/min/1.73 m2 with proteinuria);
Those who are considered by the researcher to be poor compliance or unable to complete this research well.
Clareo Health | An Observational Cohort Study to Obese Patients With Weight Cycling
