Prior immunization with HPV-vaccine (Cervarix, Gardasil-4, Gardasil-9)

Currently pregnant or breastfeeding

Immunedeficiency disease/condition or cancer that causes clinically significant immunosuppression

Known HIV infection

Chemotherapy (current or within 12 months) or currently taking a medication that causes clinically significant immunosuppression.

Unstable medical condition (e.g., malignant hypertension, poorly controlled diabetes)

Known allergy to vaccine components

Prior history of HPV-associated cancer

Any medical condition which, in the opinion of the investigator, may compromise the subject's ability to safely complete the study.

Immunogenicity of Fractional Dose of the HPV Vaccines