Efficacy and Safety of JT001 (VV116) Compared With Favipiravir

Exclusion Criteria

• •1. Participants who are judged by the investigator as likely to progress to critical COVID-19 prior to randomization.
• •2. Participants who require mechanical ventilation or anticipated impending need for mechanical ventilation
• •3. Participants who are suspected or proven serious, active bacterial, fungal, viral, or other infection (besides COVID-19) that in the opinion of the investigator could constitute a risk when taking intervention
• •4. Participants who have eye disease (such as inflammation, Vessel deformity, retinal hemorrhage or decollement, optic nerve lesion, or fundus lesion)
• •5. Participants who have any of the following conditions when screening:
• •* ALT or AST\>1.5 ULN
• •* Systolic blood pressure \< 90 mm Hg
• •* Diastolic blood pressure \< 60 mm Hg
• •* Requiring vasopressors
• •* Multi-organ dysfunction/failure
• •6. Participants who have known allergies to any of the components used in the formulation of the interventions
• •7. Any medical condition, which in the opinion of the Investigator, will compromise the safety of the participant
• •8. Participants who have received a SARS-CoV-2 monoclonal antibody treatment or prevention, or antiviral treatment (including the investigational treatment)
• •9. Participants who have received convalescent COVID-19 plasma treatment
• •10. Participants who have received SARS-CoV-2 vaccine prior to randomization.
• •11. Participants who have participated, within the last 30 days, in a clinical study involving an investigational intervention. If the previous investigational intervention has a long half-life, 5 half-lives or 30 days, whichever is longer, should have passed
• •12. Participants who are concurrently enrolled in any other type of medical research judged not to be scientifically or medically compatible with this study
• •13. Female who is pregnant or breast-feeding or plan to be pregnant within this study period
• •14. Male whose wife or partner plan to be pregnant within this study period