Age

18–65

Sex

ALL

Healthy volunteers

Accepted

For all participants
1. Able to provide informed consent
2. Visual acuity of 20/100 in at least one eye (corrective glasses, contact lenses, surgery etc. are permitted)
For patients only
1. Confirmed diagnosis of CIS with abnormal MRI or RRMS
2. Neurological condition is medically stable during the study visit

For all participants:
1. Evidence or medical history of psychiatric issues, which are known to also affect movements and oculomotor control.
2. Aged above 65 or less than 18 years of age.
3. Presence of comorbid neurological conditions to avoid eye movement anomaly confounds (Strabismus, cranial nerve palsy, stroke-causing hemianopsia).
4. Diagnosis of macular edema or other pre-existing ocular conditions that would prevent from performing the eye movement assessments.
For healthy controls only:
1. Evidence or history of significant neurological disorder (Multiple Sclerosis, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Dementia)

Implementation of a Novel Functional Eye-Tracking Biomarker for Multiple Sclerosis