Home-based Remote Digital Monitoring to Assess ALS Progression (Track ALS)

Inclusion Criteria

• •1. Male or female, age 18 to 90.
• •2. Diagnosed with definite, probable, or possible ALS according to the modified El Escorial Criteria (EEC) or diagnosed with ALS using the Gold Coast Criteria.
• •3. Must be able to ambulate independently at the time of enrollment, with or without the use of foot braces or cane.
• •4. A vital capacity score of ≥40% of the predicted value (at last known in-person visit and if available).
• •5. Intelligible speech with occasional repetition.
• •6. Willingness and medical ability to comply with scheduled visits and study procedures.
• •7. Ability to understand the purpose and risks of the study and provide signed and dated informed consent and authorization to use protected health information (PHI).
• •8. Possession of a smartphone, and willingness to install study apps on it.
• •9. Continuous internet access at home, with stable broadband internet access.
• •10. Sufficiently proficient in English to understand and complete questionnaires and follow instructions using smartphone apps.