Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Centre Leon Berard
Age
35–74
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
35-74 years of age
At increased risk for developing colorectal cancer (CRC), defined here as having a positive faecal immunochemical test (FIT), or family history or symptoms for CRC and identified adenomas but CRC negative during the colonoscopy
Volunteer and available to get involved in the project throughout the duration of the study,
Be able to provide informed consent
Having health insurance (Affiliated to the French social security)
Score on the adherence to the WCRF recommendations lower or equal to 6 out of 9 (the WCRF score will be assessed based on a short lifestyle questionnaire, annex 1)
Able to read, write and understand French language
You may not be if
On a strict diet such as meal replacements, diets for co-morbidities such as diabetes
Lacking mobility due to physical constraints (e.g. handicap that is not compatible with physical activities, uncontrolled cardiovascular diseases/hypertension)
Planned extensive intestinal surgery such as colectomy or surgical resection of the colon
Use of any systemic antibiotics, antifungals, antivirals, or antiparasitics in the past 3 months
Use of probiotic medications in the past 3 months
History or existence of a primary cancer (apart from an in-situ cancer whatever the location and / or of a cutaneous basal cell cancer and / or of a CRC in complete remission for more than 5 years)
In a state of severe malnutrition, either:
≥10% weight loss in 1 month or ≥ 15% in 6 months
Cannot be followed for medical, social, family, geographic or psychological reasons, throughout the duration of the study
Deprived of liberty by court or administrative decision
Pregnant (for women)
Concomitant participation in another study on lifestyle
Optimal lifestyle habits (WCRF score \>6) will also be excluded from the pilot study as this participants are not part of target population that could benefit significantly from lifestyle advice (short screener will be completed by patients while in waiting room for pre-colonoscopy visit).
Patients who will be positive for CRC (histological confirmation after colonoscopy) will end prematurely the study.
