Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Laval University
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
One of them
Moderate to severe COPD (forced expiratory volume in 1 second (FEV1) \< 80% predicted and FEV1/forced vital capacity (FVC) ratio \< 0.7)
Chronic interstitial lung disease such as usual interstitial pneumonitis (UIP), non-specific interstitial pneumonitis (NSIP) or hypersensitivity pneumonitis on high-resolution computed tomography
Pulmonary arterial hypertension type 1 or 4, excluding involvement secondary to collagenosis as well as secondary to congenital heart disease, as diagnosed with mean pulmonary artery pressure \> 25 mm Hg at right heart catheterization
Cystic fibrosis, as diagnosed by a positive sweat test (\>60 mmol/L) or having 2 genetic mutations known to cause cystic fibrosis.
AND having a 6-minute walking test with significant desaturation defined as a decrease in O2 saturation greater or equal to 5% with O2 saturation at the end of the walking test \< 88%
You may not be if
Exacerbation of the primary lung disease in the past 8 weeks
Exercise limiting diseases other than the primary lung disease.
Not reaching the target dyspnea score during the walking tests.
Stage 1 pulmonary sarcoidosis
History of syncope on exertion
SpO2 with effort less than 90% despite the use of 6 L of O2 per minute
Cardiac condition deemed unstable or severe (e.g. severe aortic stenosis)
Disabling or severe rheumatological or neurological condition
Participation in a pulmonary rehabilitation program within the last year
Patients with multi-resistant bacteria
Clareo Health | Effects of Automated Oxygen Titration Alone or With High Flow Nasal Therapy on Dyspnea and Exercise Tolerance
