Clareo Health | Fludarabine and Total Body Irradiation 800 Centigray (cGy) or 1125 cGy For Allogeneic Stem Cell Transplant Using Graft Versus Host Disease Prophylaxis With Post-Transplant Cyclophosphamide and Tacrolimus, Without Mycophenolate Mofetil
Fludarabine and Total Body Irradiation 800 Centigray (cGy) or 1125 cGy For Allogeneic Stem Cell Transplant Using Graft Versus Host Disease Prophylaxis With Post-Transplant Cyclophosphamide and Tacrolimus, Without Mycophenolate Mofetil
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Ronald Paquette
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patient age 18-75 years
Patient has a related donor who is at least Human Leukocyte Antigen (HLA) haploidentical, or an unrelated donor who is a most a single HLA antigen mismatch.
Patient signs the Informed Consent Form for the study
Patient has a hematologic malignancy other than myelofibrosis and meets standard criteria for allogeneic stem cell transplant.
Patient is deemed suitable to receive Fludarabine and Total Body Irradiation (Flu/TBI) 1125 or Flu/TBI 800 conditioning regimen as standard of care transplant
Donor is willing to donate peripheral blood stem cells
You may not be if
Patient has a diagnosis of myelofibrosis
Patient has high titer antibodies against one or more donor HLA antigens
Patient has undergone prior autologous or allogeneic stem cell transplant.
Inability to collect sufficient peripheral blood stem cells from the donor
