The First Affiliated Hospital of Zhengzhou University
Zhejiang University
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age more than 18 years old, no gender limit.
According to the Diagnosis and Treatment of Primary Lung Cancer (2018 edition), non-small cell lung cancer (NSCLC) was diagnosed by histopathology.
Tumor Node Metastasis (TNM) staging is II-III.
According to the National Comprehensive Cancer Network (NCCN) guidelines, patients who had failed, refused, or were not suitable for standard treatment (surgery, chemoradiotherapy, targeted) after consultation.
Eastern Cooperative Oncology Group (ECOG), Performance Status (PS) Score ≤ 2.
Estimated survival time is more than 3 months.
The patient has signed informed consent.
You may not be if
The patient has previously received interventional therapy \[iodine seed implantation, ablation, bronchial arterial chemoembolization (BACE) therapy\], or received immunotherapy during the first-line standard treatment.
The patient is accompanied by other malignant tumors and had not been cured.
White blood cell \< 3×10\*9/L, absolute value of neutrophils \< 1.5×10\*9/L, neutrophil/lymphocyte ratio ≥ 3, platelet count \< 50×10\*9/L, hemoglobin concentration \< 90 g/L.
Liver and kidney dysfunction (creatinine \> 176.8 μmol/L; aspartate aminotransferase (AST) and/or alanine aminotransferase (ALT) \> 2 times the upper limit of normal).
Uncorrectable coagulopathy or active hemoptysis.
Patient with active infections requires antibiotic treatment.
Patient has uncontrollable hypertension, diabetes, and cardiovascular disease with obvious symptoms.
