Groupement Interrégional de Recherche Clinique et d'Innovation
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Patients with localized breast or gynecological cancer treated as curative adjuvant and/or neoadjuvant chemotherapy and/or adjuvant radiotherapy. These treatments must have been completed within 6 months of inclusion.
* Patient reporting a chronic, stable fatigue state at investigator assessment, defined as a fatigue score ≥ 4 on the visual analog scale rated up to 10, experienced for at least one month
* Maintenance therapy with hormone therapy or other maintenance therapy (trastuzumab, bevacizumab…) is allowed before and/or during the study (except for pembrolizumab, abemaciclib and PARP inhibitors, which are not authorized)
* Patient 18 years of age or older
* Effective contraception in women of childbearing age
* Patient affiliated to a social security plan
* Signed informed consent
You may not be if
Other identified causes of fatigue (anemia of grade \> 2, underlying chronic disease known to be associated with fatigue)
Metastatic breast or gynecological cancer
Ongoing treatment with a tyrosine kinase inhibitor or other P-gp transported molecule or Pembrolizumab or PARP inhibitors
Patient requiring oral diabetes therapy
Regular intake of Vitamin C (in addition to what is provided by the diet)
Patients with chronic pain requiring daily treatment with analgesics, anti-inflammatory drugs or corticosteroids
Consumption of ginseng-based products in the month prior to inclusion
Hypersensitivity to any of the components of Qiseng or placebo
Pregnant or breastfeeding patient
Simultaneous participation in another therapeutic clinical trial (trial using an experimental product)
Patient deprived of liberty, under guardianship or curatorship
Patient unable to undergo the medical follow-up of the trial for geographical, social or psychopathological reasons
History of any other malignant disease during the last 3 years, except for skin cancer other than melanoma, carcinoma in situ of the uterus. Any other solid tumor or lymphoma (without bone marrow involvement) must have been treated and show no signs of recurrence for at least 3 years
Clareo Health | Evaluation of the Impact of Taking American Ginseng for 8 Weeks on Fatigue in Patients Treated for Localized Breast or Gynecological Cancer
